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(See Holford et al, 2013, for parameters in neonates and children.) Knowing the relationship between dose, drug concentration, and effects allows the clinician to take into account the various pathologic and physiologic features of a particular patient that make him or her different from the average individual in responding to a drug

Normal vitamin B12 levels do not change with age, so theres no need to look for a different cutoff as people get older

When combined, the SNAC allows oral cyanocobalamin to bypass the usual B12 absorption pathways , which are often impaired in people with B12 deficiency

Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS) are available upon request to support compliance with European research standards

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